Genetics:

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Lindy Barrett, PhD

Senior Group Leader, Research Scientist

Broad Institute | Stanley Center

pluripotent stem cell biology, genome-engineering technologies, in vitro differentiation

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Mark Bear, PhD

Investigator, Howard Hughes Medical Institute; Professor of Neuroscience, MIT

Bear Lab

Synaptic plasticity in cerebral cortex and hippocampus, autism

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Deborah Blacker, MD, ScD

Professor of Psychiatry, Harvard Medical School
Assistant Vice Chair for Research, Dept. of Psychiatry, MGH
Professor in the Department of Epidemiology, Harvard School of Public Health

Gerontology Research Unit

Epidemiology and genetics of mental illness and psychiatric research methods

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Hans Breiter, MD

Co-Director, MGH Translational Center for Prescription Drug Abuse
Assistant Professor of Psychiatry, Harvard Medical School

Phenotype Genome Project

neural circuitry of aversive and reward processing; interface of pain and substance abuse; mathematical modeling, clinical phenotyping, structural and functional imaging, genetics

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Joshua Buckholtz, PhD

Assistant Professor of Psychology, Harvard University

The Systems Neuroscience of Psychopathology Laboratory

Self control, reward systems and psychopathology

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Bill Carlezon, MA, PhD

Career Mentor

Chief, Division of Basic Neuroscience, McLean Hospital
Director, Behavioral Genetics Laboratory, McLean Hospital
Professor of Psychiatry, Harvard Medical School

Behavioral Genetics Laboratory

Molecular basis of depressive disorders, as well as the co-morbidity of depression and other disorders including anxiety, PTSD, and substance abuse

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Elena Chartoff, PhD

Director, Neurobiology of Motivated Behavior Laboratory, McLean Hospital
Assistant Professor of Psychiatry, Harvard Medical School

Chartoff Lab: Neurobiology of Motivated Behavior Laboratory

Molecular and behavioral techniques and focuses on the study of drug dependence

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Jeff Cottrell, PhD

Director of Translational Research, Stanley Center for Psychiatric Research, Broad Institute

Translation of research on the genetics of psychiatric disease into strategies for the development of novel, mechanism-based therapeutics.

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Joseph Coyle, MD

Career Mentor

Director, Laboratory for Psychiatric and Molecular Neuroscience, McLean Hospital
Eben S. Draper Professor of Psychiatry, Harvard Medical School

Laboratory for Psychiatric and Molecular Neuroscience

translational research on the neurobiology of neuropsychiatric disorders with a particular emphasis on the role of glutamatergic neurotransmission

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Mark Daly, PhD

Associate Professor of Medicine, HMS
Chief, Analytic and Translational Unit of the Center for Human Genetic Research, MGH
Senior Associate Member, The Broad Institute of MIT and Harvard

Analytic and Translational Genetics Unit

genetic epidemiology, creation of haplotype maps in mice and humans

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Alysa Doyle, PhD

Assistant Professor of Psychiatry, HMS

Center for Genomic Medicine and Director of Research at the Learning and Emotional Assessment Program

Contributing to and leveraging genetic discoveries in order to clarify the complex risk mechanisms that lead to neuropsychiatric illness across the lifespan.

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Kevin Eggan, PhD

Professor of Stem Cell and Regenerative Biology, Harvard University

Eggan Lab

Mechanisms of motor neuron degeneration.

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Gordon Fishell, PhD

Member of the Faculty of Neurobiology, Harvard University Blavatnik Institute

Fishell Lab

Embyronic specification of interneurons, interneuron integration and synapse formation, and interneuron function and dysfunction.

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Daniel Geller, M.D.

Director, Pediatric OCD and Tic Disorder Program, MGH; Associate Professor of Psychiatry, HMS

Pediatric Obsessive Compulsive Disorder (OCD) Program

pediatric obsessive-compulsive disorder and tic disorders; genetics of OCD

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Jill Goldstein, Ph.D.

Director of Research at the Connors Center for Women's Health and Gender Biology, BWH; Professor of Psychiatry and Medicine, HMS

Clinical Neuroscience Lab for Sex Differences in the Brain

gender differences in psychiatric and medical disorders

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Ann Graybiel, PhD

Professor, Department of Brain and Cognitive Sciences, MIT
Investigator, McGovern Institute

Graybiel Laboratory

habit formation, neurodegeneration, basal ganglia

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Steve Haggarty, PhD

Director, Chemical Neurobiology for the Stanley Center for Psychiatric Research at the Broad Institute
Assistant Professor of Neurology at HMS, Assistant in Neuroscience at MGH Center for Human Genetic Research
Affiliate Faculty member of the Harvard Stem Cell Institute

Chemical Genomics of Neuropsychiatric & Neurological Disease

Center for Human Genetic Research

molecular mechanisms underlying neuroplasticity, use of synthetic chemistry and genetics to investigate neurocircuitry underlying mood and memory

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Myriam Heiman, PhD

Assistant Professor of Neuroscience, MIT
Investigator, Broad Institute

Heiman Lab

striatum, neurodegeneration, neuronal profiling

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James Hudson, MD, ScD, SM

Director, Biological Psychiatry Laboratory, McLean Hospital
Professor of Psychiatry, Harvard Medical School

Biological Psychiatry Laboratory

Alcohol and Drug Abuse Clinical Research Center

genetic epidemiology of eating disorders, mood disorders, fibromyalgia, personality disorders, and substance use disorders. Pharmacologic treatment studies for psychiatric disorders and pain syndromes.

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Karestan Koenen, MA, PhD

Professor of Psychiatric Epidemiology

Lee Kum Sheung, Center for Health and Happiness, Harvard T.H. Chan School of Public Health

Genetic factors of PTSD development, and how trauma and PTSD influence weight gain and long-term physical health.

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Kasper Lage, PhD

Director of Bioinformatics at MGH; Associate Professor at HMS

Bioinformatics, interpreting large genomic datasets with the aim of informing biology and medicine, genomic datasets, surgery, genetic datasets to deduce networks driving congenital heart diseases, autoimmune disorders, and schizophrenia

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Deborah Levy, Ph.D.

Director, Psychology Research Laboratory, McLean; Associate Professor of Psychology, Department of Psychiatry, HMS

Psychology Research Laboratory

clinical phenotyping and endophenotyping (eye tracking dysfunction, thought disorder, craniofacial dysmorphology) in studies of the genetics of schizophrenia and other psychotic disorders

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Brad Lowell, MD, PhD

Director of Transgenic Core, Boston Obesity Nutrition Research Center, BIDMC
Professor of Medicine, BIDMC

Lowell Lab The Neural Basis for Homeostasis and Motivational Drives to Consume Food, Water and Salt

Use of transgenic and gene knockout techniques in the study of obesity and energy metabolism

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Steve McCarroll, PhD

Director of Genetics, Stanley Center for Psychiatric Research at the Broad Institute
Assistant Professor of Genetics, Harvard Medical School

McCarroll Genetics Lab

genetic structural variation and links to molecular phenotypes and disease risk

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Benjamin Neale, PhD

Assistant Professor, Harvard Medical School
Associate Member, Broad Institute
Director of Population Genetics, Stanley Center for Psychiatric Research, Broad Institute

Neale Lab

Statistical methodology for genetic studies, with particular focus on ADHD, Autism, and Schizophrenia.

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David Pauls, PhD

Director, Psychiatric and Neurodevelopmental Genetics Unit (PNGU), MGH
Professor of Psychiatry, Harvard Medical School

Psychiatric & Neurodevelopmental Genetics Unit

genetics of child neuropsychiatric disorders, inheritance of the Gilles de la Tourette Syndrome (GTS), OCD, autism

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Roy Perlis, MD, MSc

Director, Psychiatry Center for Experimental Drugs and Diagnostics, MGH
Associate Director, Psychiatric Genetics Program in Mood and Anxiety Disorders, MGH
Associate Professor of Psychiatry, Harvard Medical School

MGH Psychiatry Center for Quantitative Health

Patient-derived cellular models of disease using induced pluripotent stem cells; pharmacogenomics and clinical risk stratification; proof-of-concept/first-in-human clinical trials

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Elise Robinson, ScD

Assistant Professor of Epidemiology at the Harvard T.H. Chan School of Public Health

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Joshua Roffman, MD

Assistant Professor Psychiatry, MGH
Director, Brain Genomics Laboratory, MGH
Investigator, Schizophrenia Clinical and Research Program (SCRP), MGH

Psychiatric Neuroimaging Program

Schizophrenia, genetic links to schizophrenic symptoms

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Jerrold F. Rosenbaum, MD

Chief of Psychiatry, MGH
President & Executive Director, Mood and Anxiety Disorders Institute (MADI), MGH
Stanley Cobb Professor of Psychiatry, Harvard Medical School

Mood and Anxiety Disorders Institute (MADI)

treatment resistant depression, anxiety disorders, genetic and temperamental links to anxiety and mood disorders

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Amar Sahay, PhD

Assistant Professor of Psychiatry, HMS
Principal Faculty, Stem Cell Institute, Harvard
Assistant Professor, Center for Regenerative Medicine Psychiatric and Neurodevelopmental Genetics Unit (PNGU) Center for Human Genetic Research, MGH

Sahay Lab

Impact of adult stem cell hippocampal growth on mood and cognition; neural bases of psychiatric disorders

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Morgan Sheng, MD, PhD

Co-director of the Broad’s Stanley Center for Psychiatric Research

Morgan Sheng at Broad Institute

neuroscience, major diseases of the nervous system, Alzheimer’s and Parkinson’s diseases, molecular mechanisms underlying the structure and plasticity of synapses and the molecular-cell biology of neurodegeneration

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Jordan Smoller, M.D., Sc.D.

Broad/MGH, Dept. of Psychiatry

Professor of Psychiatry, HMS; Professor, Department of Epidemiology, Harvard School of Public Health; Associate Chief for Research, Department of Psychiatry, MGH; Director, Psychiatric Genetics, MGH; Director, Psychiatric and Neurodevelopmental Genetics Unit (PNGU), MGH; Co-Director, Genetics and Genomics Unit Clinical Research Program, MGH; Associate Member, Broad Institute; Senior Scientist, Stanley Center for Psychiatric Research, Broad/MIT

Psychiatric and Neurodevelopmental Genetics Unit

psychiatric and genetic epidemiology, clinical psychiatric research, statistical genetics, linage and association studies, imaging genetics, and pharmacogenetics. Design and conduct of psychiatric genetic studies, including studies of behavioral and neuroimaging intermediate phenotypes.

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Kevin Spencer, PhD

Research Health Scientist, VA Boston Healthcare System
Assistant Professor of Psychiatry, Harvard Medical School

Neural Dynamics Laboratory

neural dynamics of processing, perception, and attention, especially in schizophrenia

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Beth Stevens, PhD

Institute Member, Broad Institute; Associate Professor at HMS; Research Associate in Neurobiology at BCH

uncovering the role that microglial cells, the immune cells of the central nervous system, and their connectivity play in neurodevelopmental and neuropsychiatric disorders

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Mriganka Sur, PhD, FRS

Paul E. and Liliah Newton Professor of Neuroscience, Brain & Cognitive Sciences, MIT
Director, Simons Center for the Social Brain
Investigator, Picower Institute for Learning and Memory, MIT

The Sur Lab

cerebral cortex, development, plasticity and dynamics, brain disorders

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Frank I. Tarazi, MBBS, PhD, MBA

Director, Psychiatric Neuroscience Laboratory, McLean Hospital
Associate Professor of Psychiatry, Harvard Medical School

Psychiatric Neuroscience Laboratory

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Susumu Tonegawa, PhD

Director, Riken-MIT Center for Neural Circuit Genetics
Picower Professor, Department of Biology and Neuroscience, MIT
Investigator, Howard Hughes Medical Institute
Professor of Neuroscience, MIT

Tonegawa Lab

learning and memory, mental retardation and psychiatric diseases, genetic engineering

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Li-Huei Tsai, PhD

Picower Professor of Neuroscience, MIT
Investigator, Howard Hughes Medical Institute
Senior Associate Member, Department of Brain and Cognitive Sciences, MIT

Tsai Lab at MIT

epigenetic regulation of learning and memory, alzheimer's disease, neurogenesis

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Feng Zhang, PhD

Institute Member, Broad Institute, MIT
Investigator, McGovern Instititue for Brain Research, MIT
Assistant Professor of Neuroscience, MIT

The Zhang Lab

neuropsychiatric diseases, synthetic biology, neuroengineering